Development of 1-(substituted benzofuran-2-yl)-3-(halogen-substituted phenyl)prop-2-en-1-ones as potent, reversible, and selective MAO-B inhibitors for Parkinson’s Disease

Ten halogenated benzofuran derivatives (BF1–BF10) were synthesized and evaluated for their inhibitory activity against monoamine oxidase isoforms. All compoun...